Multydisciplinary approach to the diagnosis of mesothelioma
DOI:
https://doi.org/10.24197/cl.29.2024.52-58Keywords:
mesothelioma, cells, pleural effusionAbstract
Mesothelioma is one of the most common tumors of lung and breast origin, with a high prevalence of secondary pleural effusion.
We present the case of a middle-aged woman who required diagnostic thoracentesis after a general worsening and dyspnea on slight exertion that she had been experiencing for more than 1 month. When analyzing the pleural fluid, the finding of medium-large, multinuclear, vacuolated cell clusters that form accumulations was notable. This finding favored the extension of different anatomopathological and radiological studies performed on the patient, leading to a suspicion of renal and left pleural neoplasia.
The following month, another thoracentesis was performed after the presence of right pleural effusion, again observing the same previous cellular component under the microscope. An immunohistochemical study was performed, which was complemented with a biopsy from which a cell block was performed. Finally, thanks to multidisciplinary work, the patient was diagnosed with malignant pleural mesothelioma of epithelioid morphology.
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Copyright (c) 2024 Marta Capilla Diez, Paula Bayo Juanas, María Lorena Navas Gómez, Manuel Baladrón Segura, María Miguel Lucero Salaverry, Sara Anabel Díaz Villareal
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