Review of the clinical utility of the serum proteinogram
DOI:
https://doi.org/10.24197/cl.29.2024.32-42Abstract
The protein electrophoresis test is one of the routine procedures performed in the clinical laboratory. Traditionally, it has been used as a biochemical indicator in various clinical conditions such as liver cirrhosis, nephrotic syndrome, and different inflammatory processes. Currently, its primary use focuses on the detection and monitoring of monoclonal gammopathies due to its high clinical sensitivity, as it has been shown that other methods are more suitable for the individual quantification of proteins.
Downloads
References
- Rao, L. V., & Snyder, L. M. (2021). Wallach Interpretación clínica de pruebas diagnósticas [electronic resource] (11a. ed.). Wolters Kluwer.
- Arévalo Serrano, J., Balsa Barro, JA, González Carro, PS, Pascual Izquierdo, C., Sánchez Nievas, G., Tena Gómez, D., Rodríguez García, JL, e coord., Rodríguez García, JL, & e coordinar. (2013). Alteraciones analíticas: diagnóstico, tratamiento médico . Marbán.
- McPherson, R. A., Pincus, R. M. (2022). Henry. Diagnóstico clínico y técnicas de laboratorio (24ª. ed.). Elsevier.
- D. Pérez Surribas, M.C Cárdenas Fernández, E. Z. M. Recomendaciones sobre la separación electroforética de las proteínas plasmáticas en el suero. Sociedad Española de Bioquímica Clínica y Patología Molecular. (2015).
- Cidoncha A., Pérez E., Vinuesa A., Zaro M.J., Zafra A, V. C. El proteinograma en la práctica clínica. Med. Integr. 38, 127-132 (2001).
- O’Connell, T. X., Horita, T. J. & Kasravi, B. Understanding and interpreting serum protein electrophoresis. Am. Fam. Physician 71, 105-112 (2005).
- Cámara Hernández, V. & González Pereira, N. Decisiones inteligentes desde el laboratorio: de elegir sabiamente a no hacer. 2ª Edición. (2021).
- Murray D.L. Laboratory methods for analyzing monoclonal proteins. In: UpToDate, Rajkumar SV (Ed). https://www-uptodate-com.na-cdib.a17.csinet.es/contents/laboratory-methods-for-analyzing-monoclonal-proteins
- Cárdenas Fernández M.C., Pérez Surribas D., Zapico Muñiz E. Electroforesis de proteínas séricas. Ficha Interv Rep Proteinograma. Versión 1. Noviembre 2019. Sociedad Española de Medicina de Laboratorio (SEQCML).
- Ruiz de Adana Pérez, R. Indicaciones e interpretación del proteinograma. FMC Form. Medica Contin. en Aten. Primaria 26, 263-270 (2019).
- Divulgación de Iniciativas para Analizar la Adecuación en Salud (DianaSalud). http://www.dianasalud.com/
Downloads
Published
Issue
Section
License
Copyright (c) 2024 Marta Capilla Diez, María Lorena Navas Gómez, Manuel Baladrón Segura, Patricia Ramos Mayordomo, Sara Martín Gabriel, Nuria Alonso Castillejos

This work is licensed under a Creative Commons Attribution 4.0 International License.
The articles published at Clínica will have a Creative Commons Attribution 4.0 International License (CC BY 4.0).
The journal allows the authors to retain publishing rights. Authors may reprint their articles in other media without having to request authorization, provided they indicate that the article was originally published in Clínica.
